HIV can develop resistance to CRISPR/Cas9
Thursday, April 7, 2016 - 22:42
in Health & Medicine
The CRISPR/Cas9 gene-editing platform may need more tweaking before it can be used as an effective antiviral, reports a new study. Researchers who used CRISPR/Cas9 to mutate HIV-1 within cellular DNA found that while single mutations can inhibit viral replication, some also led to unexpected resistance. The researchers believe targeting multiple viral DNA regions may be necessary for the potential antiviral aspect of CRISPR/Cas9 to be effective.