New methods of enhancing efficiency of genetic engineering in mice, rats
Thursday, March 24, 2016 - 10:00
in Biology & Nature
Two new gene modification methods have been developed: lsODN (long single-stranded oligodeoxynucleotide) and 2H2OP (two-hit two-oligo with plasmid). These methods use CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) -Cas systems and ssODN (single-stranded oligodeoxynucleotide).