Obesity breakthrough: Metabolic master switch prompts fat cells to store or burn fat

Wednesday, August 19, 2015 - 21:00 in Health & Medicine

Obesity is one of the biggest public health challenges of the 21st century. Affecting more than 500 million people worldwide, obesity costs at least $200 billion each year in the United States alone, and contributes to potentially fatal disorders such as cardiovascular disease, type 2 diabetes, and cancer. Scientists have now revealed the mechanism underlying the genomic region most strongly associated with obesity. The findings uncover a genetic circuit that controls whether our bodies burn or store fat. Manipulating that genetic circuit may offer a new approach for obesity treatments.

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