Testosterone in healthy men increases their brains' response to threat

Testosterone, a steroid hormone, is well known to contribute to aggressive behavior in males, but the neural circuits through which testosterone exerts these effects have not been clear. Prior studies found that the administration of a single dose of testosterone influenced brain circuit function. Surprisingly, however, these studies were conducted exclusively in women. Researchers have now sought to rectify this gap by conducting a study of the effects of testosterone on the brain’s response to threat cues in healthy men.

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