Hemorrhagic Fevers Can Be Caused by Body's Antiviral Interferon Response

Virologists and immunologists have found a major clue to the mystery of “hemorrhagic fever” syndromes. The team showed that Interferon Type I immune proteins are key drivers of a viral syndrome in mice that closely mimics human hemorrhagic fevers. Hemorrhagic fevers caused by Lassa, dengue and other viruses affect more than one million people annually and are often fatal, yet scientists, until now, have never understood why only some virus-infected people come down with the disease and others do not.

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