Gene sequencing project discovers mutations tied to deadly brain tumors in young children

New mutations in pediatric brain tumors known as high-grade gliomas, which most often occur in the youngest patients, have been discovered by researchers. The discoveries stem from the most comprehensive effort yet to identify the genetic missteps driving these deadly tumors. The results provide desperately needed drug development leads, particularly for agents that target the underlying mutations. This and other studies show these mutations often differ based on patient age.

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