Proteins that deliver leucine to prostate cancer cells are therapeutic targets
Friday, September 20, 2013 - 11:30
in Health & Medicine
Like normal cells, cancer cells require amino acids for growth, maintenance, and cell signaling, and L-type amino acid transporters (LATs) are the delivery vehicles that supply them. Metastatic, castration-resistant prostate cancer cells are highly dependent on LATs to deliver the amino acid leucine that the cells need for growth and proliferation.