B cells, precursors of autoantibody-secreting cells, have emerged as promising new therapeutic targets in autoimmune diseases, including rheumatoid arthritis.
... to fuel different types of cancer through multiple molecular pathways, making it an important therapeutic target," said Mehta, whose lab also has connected TG2 overexpression to drug-resistant and ...
Researchers at Hospital for Special Surgery have identified a potential new therapeutic target that could be used to treat inflammatory disorders, such as rheumatoid arthritis. The study, published ...
A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from gene, "Seven-In-Absentia," according to ...
A possible new therapeutic target for pancreatic cancer, the most lethal form of human cancer, has been identified in the proteins whose DNA recipe comes from the gene, "Seven-In-Absentia."
... in regulating pain perception, also seems to influence learning and memory. The new findings could help explain the mechanisms of Alzheimer's disease and yield a potential new therapeutic target.
... active in bone metastases, but previously unexplored in primary bone tumors, is a potential therapeutic target in osteosarcoma, investigators from The University of Texas M. D. Anderson Cancer Center ...
A receptor known to be active in bone metastases, but previously unexplored in primary bone tumors, is a potential therapeutic target in osteosarcoma, investigators report in Cancer Research.
... phase.
This is the first report suggesting an inhibitory role of AhR agonists on human GC cell growth. Furthermore, the present findings suggest that AhR may be a potential therapeutic target for GC.
... In HSC-T6 cells transfected with RNAi targeted to p90RSK, the expression of collagen type I was ... new view of p90RSK on liver fibrosis, and thus may provide a new therapeutic target to liver fibrosis.
... suggests that zinc may be pointing the way to new therapeutic targets for fighting infections. Specifically, scientists ... work points toward new possible targets for entirely new drugs to help augment ...
... with Idiopathic Pulmonary Fibrosis.
"It remains to be seen if fibrosis is reversible," he said. "But therapeutic targeting of this pathway this may allow us to halt the progression of fibrosis and ...
HAMBURG, Germany, Aug. 31 (UPI) -- German researchers say they determined viral polymerase might provide a new therapeutic target for host-adapted avian influenza.
... molecules—called chondroitin sulfate proteoglycans (CSPGs)—bind to the surface of neurons, exposing a novel therapeutic target. Their findings appear online in the journal Science on Oct. 15.
"The ...
... overexpression and gene amplification is a rare event. They concluded that routine testing and therapeutic targeting of HER2 does not seem to be useful in patients with BTC, while targeting EGFR may ...
