Gene mutation may have effect on benefit of aspirin use for colorectal cancer
Tuesday, June 25, 2013 - 19:00
in Health & Medicine
In two large studies, the association between aspirin use and risk of colorectal cancer was affected by mutation of the gene BRAF, with regular aspirin use associated with a lower risk of BRAF-wild-type colorectal cancer but not with risk of BRAF-mutated cancer, findings that suggest that BRAF-mutant colon tumor cells may be less sensitive to the effect of aspirin, according to a new study.