‘Stressed’ bacteria become resistant to antibiotics
Thursday, February 21, 2013 - 21:30
in Health & Medicine
Bacteria become resistant to antibiotics when stressed, finds new research. In particular E. coli grown at high temperatures become resistant to rifampicin. It is generally thought that antibiotic resistance is costly to maintain, for example mutations which reduce antibiotic uptake also restrict the amount of nutrients entering the cell. Consequently in the absence of antibiotics non-resistant bacteria will out-compete the resistant ones. However researchers have discovered that by putting bacteria under stress, by growing them at a high temperature, the bacteria could spontaneously develop resistance to the antibiotic rifampicin.