Tiny probes shine brightly to reveal the location of targeted tissues

Nanostructures called BRIGHTs seek out biomarkers on cells and then beam brightly to reveal their locations. In the tiny gap between the gold skin and the gold core of the nanoparticle, there is an electromagnetic hot spot that lights up the reporter molecules trapped there. BRIGHTs, which shine about 1.7 x 10^11 more brightly than isolated Raman reporters, are intended for use in noinvasive bioimaging.

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