Engineered, drug-secreting blood vessels reverse anemia in mice
Wednesday, November 16, 2011 - 04:30
in Health & Medicine
Patients who rely on recombinant, protein-based drugs must often endure frequent injections, often several times a week, or intravenous therapy. Researchers have demonstrated the possibility that blood vessels, made from genetically engineered cells, could secrete the drug on demand directly into the bloodstream. In a new study, they provide proof-of-concept, reversing anemia in mice with engineered vessels secreting erythropoietin (EPO).