HIV: Cell-penetrating peptides for drug delivery act like a Swiss Army Knife

Scientists have identified how HIV TAT peptides can have multiple interactions with the membrane, the actin cytoskeleton, and specific cell-surface receptors to produce multiple pathways of translocation under different conditions. Moreover, because they now know how cell penetrating peptides work, it is possible to have a general recipe for reprogramming normal peptides into cell penetrating peptides.

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