X-ray protein probe leads to potential anticancer tactic

Monday, September 12, 2011 - 15:31 in Biology & Nature

Researchers have identified a new type of potential anticancer drug. The compound, named FOBISIN, targets 14-3-3 proteins, important for the runaway growth of cancer cells. The researchers were using X-rays to see how FOBISIN fits into the clamp-shaped 14-3-3 protein structure. Unexpectedly, the X-rays induced the compound to be permanently bonded to the protein.

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