Mutation links inherited narcolepsy with multiple neuropsychiatric disorders

Narcolepsy is a rare disorder characterized by an excessive urge to sleep at inappropriate times and places. Narcoleptics are also often subject to "cataplexy," a sudden muscle weakness that is triggered by strong emotions. Although most cases of narcolepsy are thought to be caused by complex mechanisms, a small percentage of cases are associated with unidentified inherited mutations. Now, a new study uncovers a mutation that causes narcolepsy in a large family affected by the disorder.

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