Study of metabolites reveals health implications from small molecules
Wednesday, August 31, 2011 - 21:30
in Biology & Nature
Researchers have discovered 37 new genetic variants associated with concentrations of metabolites in the blood: many of these match variants associated with diseases such as kidney disease and type 2 diabetes. The team looked for genetic influences on levels of more than 250 compounds in blood, including lipids, sugars, and amino acids. The effects of variants discovered in genome-wide association analyses can be modest and biological understanding poor: this new approach can overcome these problems.