Structural biologists reveal novel drug binding site in NMDA receptor subunit

Structural biologists have obtained a precise molecular map of the binding site for an allosteric inhibitor in a subtype of the NMDA (N-methyl-D-aspartate) receptor, which is commonly expressed in brain cells, dysfunctions of which have been implicated in depression, schizophrenia, Parkinson's and Alzheimer's diseases.

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