Gatekeepers: How microbes make it past tight spaces between cells

There are ten microbial cells for every one human cell in the body, and microbiology dogma holds that there is a tight barrier protecting the inside of the body from outside invaders, in this case bacteria. Bacterial pathogens can break this barrier to cause infection and researchers wondered how microbes get inside the host and circulate in the first place. They tested to see if microbes somehow weaken host cell defenses to enter tissues.

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