Chasing EHEC via computer: Scientists in Germany provide free access to enteric pathogen's genetic regulation data
Saturday, June 11, 2011 - 12:30
in Biology & Nature
Just a few genes make enterohaemorrhagic E. coli (EHEC) extremely dangerous to humans. If it were not for these genes, EHEC would hardly differ from harmless enteric bacteria. Bioinformatics scientists from Germany want to exploit this similarity to find starting points for effective drugs against the EHEC pathogen. In a very short time, the scientists have constructed EhecRegNet, a database and analysis platform that incorporates all known interactions between enteric E. coli genes. Using integrated simulations, genetic switches for the dangerous EHEC genes can be identified much faster and used medically. The virtual laboratory will thus help biomedical scientists and pharmacists all over the world to develop new drugs.