Sweet defence against lethal bacteria: Synthesizing a potential vaccine candidate for an antibiotic-resistant pathogen

Monday, May 30, 2011 - 11:31 in Health & Medicine

There is now a promising vaccine candidate for combating the pathogen which causes one of the most common and dangerous hospital infections. An international team of scientists has developed a vaccine based on a carbohydrate against the Clostridium difficile bacterium, which is known to cause serious gastrointestinal diseases mainly in hospitals. The sugar-based vaccine elicited a specific and effective immune response in mice. Moreover, the scientists have also discovered strong indications that the substance can stimulate the human immune system to form antibodies against the bacterium.

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