Mystery solved: How sickle hemoglobin protects against malaria

A new article is likely to help solve one of the long-standing mysteries of biomedicine. In a study that challenges currently held views, researchers unravel the molecular mechanism whereby sickle cell hemoglobin confers a survival advantage against malaria, the disease caused by Plasmodium infection. These findings open the way to new therapeutic interventions against malaria, a disease that continues to inflict tremendous medical, social and economic burdens to a large proportion of the human population.

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