HIV-1 drug resistance mutations associated with increased risk of antiretroviral treatment failure

Tuesday, April 5, 2011 - 16:30 in Health & Medicine

An analysis of data from 10 studies indicates that the presence of low frequency (also called "minority") human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly those involving nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, are significantly associated with an increased risk of first-line antiretroviral treatment failure, according to new research.

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