Pig model of cystic fibrosis improves understanding of disease
Wednesday, March 16, 2011 - 16:31
in Health & Medicine
Using a newly created pig model that genetically replicates the most common form of cystic fibrosis, researchers have now shown that the CF protein is "misprocessed" in the pigs and does not end up in the correct cellular location. This glitch leads to disease symptoms, including gastrointestinal abnormalities and lung disease in the pigs, which mimic CF in humans.