Unprecedented view of protein folding may help develop brain disease therapies

When vital proteins in our bodies are misfolded, debilitating diseases can result. If researchers could see the folding happen, they might be able to design treatments for some of these diseases. But many of our most critical proteins are folded, hidden from sight, inside tiny molecular chambers. Now researchers have gotten the first-ever peek inside one of these protein-folding chambers as the folding happened, and the folding mechanism they saw surprised them.

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