Therapeutic target for liver cancer and predictive biomarker of response identified
Monday, March 14, 2011 - 20:30
in Health & Medicine
Scientists have identified a strategy for targeted molecular therapy in liver cancer, which currently has limited treatment options and one of the worst one-year survival rates of any cancer type. The researchers' experiments reveal that up to 15 percent of liver tumors are "driven" by the hyperactivity of a gene called FGF19. Shutting down the activity of this gene with an antibody inhibited tumor growth.