Therapeutic target for liver cancer and predictive biomarker of response identified

Monday, March 14, 2011 - 20:30 in Health & Medicine

Scientists have identified a strategy for targeted molecular therapy in liver cancer, which currently has limited treatment options and one of the worst one-year survival rates of any cancer type. The researchers' experiments reveal that up to 15 percent of liver tumors are "driven" by the hyperactivity of a gene called FGF19. Shutting down the activity of this gene with an antibody inhibited tumor growth.

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