One Sleepless Night Increases Dopamine In The Human Brain

Just one night without sleep can increase the amount of the chemical dopamine in the human brain, according to new imaging research in the Journal of Neuroscience. Because drugs that increase dopamine, like amphetamines, promote wakefulness, the findings offer a potential mechanism explaining how the brain helps people stay awake despite the urge to sleep. However, the study also shows that the increase in dopamine cannot compensate for the cognitive deficits caused by sleep deprivation.

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