Scientists begin to unravel how the protein tau transitions from a soluble liquid state to solid fibrous tangles
Thursday, July 6, 2017 - 14:32
in Biology & Nature
While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons. Yet how this protein transitions from its soluble liquid state to solid fibers has remained unknown—until now.