Subtle steric differences reveal a model for Ni cross-coupling success
Monday, March 27, 2017 - 09:31
in Physics & Chemistry
A new strategy for ligand design may enable challenging metal-catalyzed cross couplings reactions that are indispensable to drug development, according to a study published in Nature Chemistry. Based on subtle differences between ligand parameters, Princeton researchers have developed a predictive model for the success of a novel Ni-catalyzed cross-coupling reaction.