Genome engineering of quantifiable protein tags

Monday, June 6, 2016 - 08:31 in Biology & Nature

Cell biologists' most notorious approach to detect and semi-quantify proteins, western blotting, could well be on its way down. Professor Sven Eyckerman (VIB/UGent) and colleagues developed a set of universal protein tags that warrant protein quantification via targeted proteomics techniques. The development and applications of these new tags - named Proteotypic peptides for Quantification by SRM (PQS) - are described in the online, open access journal Scientific Reports.

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