Protein channelrhodopsin-2 findings facilitate manufacture of bespoke optogenetic tools

Wednesday, January 7, 2015 - 09:30 in Physics & Chemistry

Researchers have shed light upon the mode of action of the light-controlled channelrhodopsin-2 with high spatiotemporal resolution. This biomolecule is used in optogenetic applications, which is deployed to control the activity of living cells with light. "The model we developed makes it possible to create customised optogenetic tools for individual applications," says Prof Dr Klaus Gerwert from the Department of Biophysics at the Ruhr-Universität Bochum. Together with colleagues at the Humboldt Universität zu Berlin from the team headed by Prof Dr Peter Hegemann, the Bochum researchers report about their finding in the magazine Angewandte Chemie.

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