Gene regulation differences between humans and chimpanzees more complex than thought

Changes in gene regulation have been used to study the evolutionary chasm that exists between humans and chimpanzees despite their largely identical DNA. However, scientists from the University of Chicago have discovered that mRNA expression levels, long considered a barometer for differences in gene regulation, often do not reflect differences in protein expression—and, therefore, biological function—between humans and chimpanzees. The work was published Oct. 17 in Science.

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