'Cowcatcher' enzyme fixes single-strand DNA

Monday, July 29, 2013 - 14:21 in Biology & Nature

Every time one of your cells divides, it exposes its most essential component to great danger: its genome, the sum total of all its genetic information, embodied in the double-stranded helix of DNA. Prior to cell division, this DNA splits into two single strands, each bearing sequences of biochemical bases that form templates for the genomes of the daughter cells. These single strands are particularly vulnerable to assaults by reactive oxygen species—toxic byproducts of respiration—that could cause changes in the genetic information they contain.

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