Solving puzzles without a picture: New algorithm assembles chromosomes from next generation sequencing data

Thursday, January 10, 2013 - 11:32 in Biology & Nature

One of the most difficult problems in the field of genomics is assembling relatively short "reads" of DNA into complete chromosomes. In a new paper published in Proceedings of the National Academy of Sciences an interdisciplinary group of genome and computer scientists has solved this problem, creating an algorithm that can rapidly create "virtual chromosomes" with no prior information about how the genome is organized.

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