Viruses' copying mechanism demystified, opening the door to new vaccine strategies

Thursday, July 19, 2012 - 11:01 in Biology & Nature

Certain kinds of viruses such as those that cause the common cold, SARS, hepatitis, and encephalitis, copy themselves using a unique mechanism, according to a team of Penn State University scientists that includes David Boehr, an assistant professor of chemistry and a co-leader of the research team. The discovery sheds light on a previously identified, but never-before-understood region of an enzyme associated with the process of replicating genetic material. The research is an important step toward the improvement of existing vaccines, as well as toward the design of vaccines against viruses that have eluded vaccination strategies in the past. The research will be published in the print issue of the journal Structure on 5 September 2012.

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