Improved method for protein sequence comparisons is faster, more accurate, sensitive

Sunday, December 25, 2011 - 19:00 in Biology & Nature

Lightning fast and yet highly sensitive: HHblits is a new software tool for protein research which promises to significantly improve the functional analysis of proteins. A team of computational biologists led by Dr. Johannes Soding of LMU's Genzentrum has developed a new sequence search method to identify proteins with similar sequences in databases that is faster and can discover twice as many evolutionarily related proteins as previous methods. From the functional and structural properties of the identified proteins conclusions can then be drawn on the properties of the protein to be analysed.

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