Spiral constriction -- how dynamin mediates cellular nutrient uptake
Tuesday, September 20, 2011 - 11:32
in Biology & Nature
Dr. Katja Falber and Professor Oliver Daumke, structural biologists at the Max Delbruck Center for Molecular Medicine (MDC) Berlin-Buch, together with researchers from Freie Universität (FU) Berlin, have determined the molecular structure of dynamin, a 'wire-puller' that mediates nutrient uptake into the cell. Since pathogens such as HIV can also enter the body's cells in this way, understanding the underlying molecular mechanisms can potentially open up new approaches for medical applications.