Tuning natural antimicrobials to improve their effectiveness at battling superbugs

Monday, August 22, 2011 - 11:31 in Health & Medicine

Ongoing research at the Institute of Food Research, which is strategically funded by BBSRC, is exploring the use of virus-produced proteins that destroy bacterial cells to combat potentially dangerous microbial infections. Bacteriophages produce endolysin proteins that specifically target certain bacteria, and IFR has been studying one that destroys Clostridium difficile, a common and dangerous source of hospital-acquired infections. New research is showing that it is possible to 'tune' these endolysin properties to increase their effectiveness and aid their development as a new weapon in the battle against superbugs.

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