A chaperone system guides tail-anchored membrane proteins to their destined membrane
Tuesday, July 5, 2011 - 09:30
in Biology & Nature
Newly synthesized proteins can only fold into their correct three dimensional structure thanks to chaperones. In case of membrane proteins chaperones do not only prevent their aggregation, but also escort them to their destination and aid in membrane insertion. The underlying molecular mechanism has now been resolved for tail-anchored membrane proteins.