Repulsion more important than cohesion in embryonic tissue separation

Tuesday, April 5, 2011 - 11:33 in Biology & Nature

Until now, adherence was thought to be the principle force responsible for the separation of the ectoderm from the mesoderm in embryonic cells. But by using high resolution imaging, researchers have now discovered that, although embryonic cells of different types will temporarily adhere when they touch, they then invariably pull apart rather violently, suggesting that direct contact between two "foreign" cells triggers a "repulsive signal."

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