New insights for a therapeutic approach in glioblastoma
Friday, March 18, 2011 - 10:00
in Health & Medicine
(PhysOrg.com) -- Scientists from the Friedrich Miescher Institute for Biomedical Research have identified a new and important molecular player in glioblastoma. The amount of the MNK1 kinase is not only dramatically increased in this devastating brain tumor, but its inhibition reduces cell proliferation and substantially sensitizes glioma cells to rapamycin. MNK1 controls the production of cancer related proteins, in particular those highly activated in malignant tumors. Their results are published today in Cancer Research.