... OGF-OGFr axis is known to regulate cell proliferation by modulating cyclin dependent kinase ... Transport through the nuclear pore and repression of cell proliferation required two of the three nuclear ...
... and suggests new directions for potential therapeutic strategies. The EGFR is closely associated with cell proliferation and survival and excessive expression, and activation of the EGFR is often ...
... applications. Marco Milán goes on to say, “this finding could provide clues about how to repress the cell proliferation signals in cancer”.
The context is relevant
Furthermore, the research has ...
... as replacing worn-out cells or repairing damage. Uncontrolled cell proliferation can lead to cancer and other disorders.
One of the most important cellular control mechanisms works through a protein ...
... the cell surface where it serves as a binding protein for variety of ligands implicated in cell proliferation, differentiation, adhesion, mitogenesis and angiogenesis. The specific binding of HB-19 to ...
... to other cell types, they say.
Inactivation of other genes disrupted embryonic stem cell proliferation. These genes were already known to have only slight influence on viability of mature cells in ...
... blood, skin or intestinal tissues.
The tiny number of stem cells in the adult spinal cord ... Meletis said.
Upon injury, ependymal cells proliferate and migrate to the injured area, producing a mass ...
... target genes inhibit cell proliferation, but those required for inhibition of cell growth were unknown. New ... species (ROS), which play important roles in cell signaling. Under genotoxic stress, ROS ...
... p53, a protein that acts in the cell nucleus to control the expression of other genes whose products can inhibit cell proliferation (increase in cell number) and cell growth (increase in cell size)...
... in growth factor proteins which signal bone cells in the area to multiply and form complex bone ... matrix does, providing scaffolding for bone cells to proliferate and form new tissue. The researchers ...
... relevant to fibrotic situations in other tissues."
The state of cell-cycle arrest known as senescence was first ... i.e. liver cell] death and stellate cell proliferation allow the production of senescent ...
... Our findings demonstrate that important signaling pathways regulating adult stem cell proliferation, migration and differentiation are evolutionarily and functionally conserved between planarians and ...
... research to appear in the October 3 issue of Cell, scientists at the Howard Hughes Medical Institute ... heal in mice. "During injury, stem cells proliferate and migrate to the affected site and replenish ...
... they've seen it at work in adult stem cells of the fruit-fly testes, so-called germ ... machinery, steering it on a course toward stem-cell over-proliferation and cancer.
The checkpoint mechanism senses ...
... NOD2-deficient mice and RNA interference. In the absence of NOD2 colonic epithelial cells proliferation was reduced and apoptosis increased, which were exacerbated when challenged with the enteric ...
