Scientists discover origin of brain immune cells

Wednesday, October 27, 2010 - 09:30 in Biology & Nature

A team of international scientists led by Dr Florent Ginhoux of the Singapore Immunology Network (SIgN) of Singapore's Agency of Science, Technology and Research (A*STAR), have made a breakthrough that could lead to a better understanding of many neurodegenerative and inflammatory brain disorders. Their work, published in top scientific journal Science, uncovered the origins of microglia, which are white blood cells specific to the brain, and showed that, in mice, microglia had a completely different origin than other white blood cells. This understanding may lead to the development of new strategies to manipulate microglia for the treatment of various brain disorders.

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