Math model of colon inflammation singles out dangerous immune cells

Scientists at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have constructed a mathematical and computational model of inflammatory bowel disease that allows researchers to simulate the cellular and molecular changes underlying chronic inflammation in humans. The model allows scientists to explore different interactions of cells in the immune system, check how these cells are linked to inflammation in the colon, and identify intervention points to perhaps stop the disease in its tracks. The work appears in the Journal of Theoretical Biology.

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