DksA polices the intersection of replication and transcription

Thursday, May 13, 2010 - 12:40 in Biology & Nature

DNA replication, the process by which a strand of DNA is copied during cell proliferation , and DNA transcription, the process by which the message in the DNA is translated into messenger RNA, involve the same "track" or DNA template. What happens when the two mechanisms are on the same track at the same time? Baylor College of Medicine researchers have identified the director -- the transcription factor DksA. A report appears in the current issue of the journal Cell.

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