Long-term treatment with proton pump inhibitor can increase weight

Friday, October 23, 2009 - 12:49 in Health & Medicine

Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all grades of GERD, making these agents the mainstay of treatment. However, the possible impact of changes in body weight(BW) or body mass index (BMI) in reflux patients while on long-term PPI therapy has not been examined.

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