Iron regulates the TLR4 inflammatory signaling pathway

Monday, October 5, 2009 - 20:14 in Health & Medicine

Iron is a micronutrient essential to the survival of both humans and disease-causing microbes. Changes in iron levels therefore affect the severity of infectious diseases. For example, individuals with mutations in their HFE gene have exceedingly high levels of iron in their liver and are more susceptible to infection with a number of microbes.

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