Resistance to antibiotics: When 1+1 is not 2

The evolution of multiple antibiotic resistances is a global and difficult problem to eradicate. Isabel Gordo, a group leader at the Instituto Gulbenkian de Ciência (IGC), Portugal, reports in the paper published in the latest issue of PLoS Genetics, that the deleterious effect associated with the acquisition of resistance by a bacteria can be suppressed by the acquisition of a new resistance to another antibiotic. These findings have direct implications for the approaches taken to tackle the problem of multi-resistance to antibiotics and in the choice of antibiotics to be administrated to patients.

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