How does microglia examine damaged synapses?
Tuesday, March 31, 2009 - 16:42
in Health & Medicine
Microglia, immune cells in the brain, is suggested to be involved in the repair of damaged brain, like a medical doctor. However, it is completely unknown how microglia diagnoses damaged circuits in an in vivo brain. Japanese group led by Professor Junichi Nabekura and Dr Hiroaki Wake of National Institute for Physiological Sciences, NIPS, Japan, successfully took a live image how microglia surveys the synapses in the intact and ischemic brains of mice by using two-photon microscopic technology. They report their finding in Journal of Neuroscience on April 1, 2009.