... of certain receptors on the surface of the nerve cell at the synapse. In particular, the new findings suggest that the protein ... -Giles. "So by understanding the initial development of synapses, we may also be getting at the molecular mechanisms underlying plasticity ...
... .1083/jcb.2008. A neuromuscular junction, or synapse, in a newborn mouse is functional but simple, with a globular ... laminin, are corralled by laminin on the muscle side of the synapse. These receptors, in turn, gather other receptors that respond ...
... . This allows the neurotransmitter to diffuse to the postsynaptic part of the synapse. Neurons send and receive information via ... into the nerve terminal. The receiving neuron on the other site of the synapse detects the neurotransmitter via receptors and converts ...
... of the nerve cell's communication units, called synapses, we are good at both. Up to now, only the receiving side of a synapse was believed to play an active role in this reorganization of the brain, which is thought to underlie our ability to learn ...
... of the nerve cell's communication units, called synapses, we are good at both. Up to now, only the receiving side of a synapse was believed to play an active role in this reorganization of the brain, which is thought to underlie our ability to learn ...
... from postsynaptic dendritic spines, prompting nearby presynaptic axons to lock on, and develop new synapses ...
... glutamate release at cortical pyramidal cell synapses were increased in mice carrying the FHM mutation ... of the FHM mutation at cortical excitatory and inhibitory synapses points to a perturbation of the excitation-inhibition balance ...
... actively reached out their processes selectively for neuronal synapses at an interval of one hour with a contact duration of 5 ... . Frequently after the prolonged survey by microglia, damaged synapses were eliminated. This is the first report to show how microglia ...
... taken a live image how microglia survey synapses in the brains of mice by using two-photon microscopic ...
... ," said Washbourne, who is a member of the UO's Institute of Neuroscience. "Synapses are initially formed during development of the nervous ... -driven instructions for synthesizing molecules responsible for synapse formation, Washbourne said. "Basically," Washbourne said, "we have found mechanisms ...
... that neuroligin is one of the first molecules to be recruited to new synapses and that it also acts as Velcro to strengthen those new connections ... formation and function, but it is only recently that a link between the two synapse-forming molecules and autism has been recognized, McAllister ...
DAVIS, Calif., June 22 (UPI) -- U.S. scientists have determined a protein called neuroligin, implicated in some forms of autism, is critical to the construction of a working synapse.
STANFORD, Calif., Oct. 12 (UPI) -- U.S. medical researchers say they've identified a molecule that plays a key role in the formation of brain synapses.
... , Sudhof noted) the mutant mice had alterations in their synapses — the gaps between nerve cells where signals ... , moreover, was confined to one of the two broad classes of synapses: excitatory, as opposed to inhibitory. "This selective change ...
... abilities as well as some brain disorders. "We know that synapses are essential for learning, memory and perception and suspect ... regulator of these important brain connections." The majority of synapses in the brain use glutamate as a neurotransmitter. While past ...