Study sheds light on angiogenesis inhibitors, points to limitations, solutions

A new generation of cancer drugs designed to starve tumors of their blood supply - called "angiogenesis inhibitors"--succeeds at first, but then promotes more invasive cancer growth -sometimes with a higher incidence of metastases, according to a new study in animals. The research clarifies similar findings in other animal studies and is consistent with some early evidence from a small number of clinical trials with cancer patients.

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